Kumar K, Toth C, Jay V
Department of Surgery, Section of Neurosurgery, Plains Health Center, University of Saskatchewan, Regina, Sask., Canada.
Pediatr Neurosurg. 1998 Aug;29(2):60-3. doi: 10.1159/000028690.
Focal, demyelinating lesions of the cerebrum mimicking brain tumors are a rare phenomenon, and even rarer in a pediatric population. We document the case of a 14-year-old female whose clinical, radiological and operative findings were strongly suggestive of glioma. However, histopathology revealed a demyelinating process. This case is significant as the lesion could not be distinguished from a glioma at any time in the presentation. At 41 months follow-up, the patient remains stable without further evidence of demyelination in other areas of the brain. Such a case suggests a cautious note for the pediatrician when presented with a similar patient and illustrates the importance of consideration of a demyelinating lesion in the differential diagnosis of a mass lesion in a pediatric population.
大脑局灶性脱髓鞘病变酷似脑肿瘤是一种罕见现象，在儿科人群中更为罕见。我们记录了一例14岁女性病例，其临床、影像学和手术结果强烈提示为胶质瘤。然而，组织病理学显示为脱髓鞘过程。该病例意义重大，因为在整个病程中该病变无法与胶质瘤区分开来。在41个月的随访中，患者病情稳定，脑部其他区域无进一步脱髓鞘迹象。这样的病例提示儿科医生在面对类似患者时要谨慎，并说明了在儿科人群中鉴别诊断肿块性病变时考虑脱髓鞘病变的重要性。
