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骨转换的生化标志物。审视反映骨状态的实验室检测。

Biochemical markers of bone turnover. A look at laboratory tests that reflect bone status.

作者信息

Rosen C J, Tenenhouse A

机构信息

Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Bangor 00401, USA.

出版信息

Postgrad Med. 1998 Oct;104(4):101-2, 107-10, 113-4. doi: 10.3810/pgm.1998.10.447.

Abstract

Chemicals in serum and urine can serve as markers for monitoring bone loss, bone reformation, and the effectiveness of therapy in patients with osteoporosis. Although not yet well recognized or readily available, tests for these markers may prove preferable to densitometry in some settings or for some patients. In the future, biochemical markers may provide important information on fracture risks as well.

摘要

血清和尿液中的化学物质可作为监测骨质疏松症患者骨质流失、骨重塑及治疗效果的标志物。尽管这些标志物检测尚未得到广泛认可,也不易获取,但在某些情况下或对某些患者而言,其检测可能比骨密度测定更具优势。未来,生化标志物或许还能提供有关骨折风险的重要信息。

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