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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine.

作者信息

Wang J C

机构信息

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

出版信息

Q Rev Biophys. 1998 May;31(2):107-44. doi: 10.1017/s0033583598003424.

DOI:10.1017/s0033583598003424
PMID:9794033
Abstract
摘要

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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine.II型DNA拓扑异构酶使一条DNA双螺旋穿过另一条DNA双螺旋：一个简单分子机器的故事。
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DNA topology: topoisomerases keep it simple.DNA拓扑结构：拓扑异构酶使其保持简单。
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Topoisomerases. In one gate, out the other.拓扑异构酶。进一扇门，出另一扇门。
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