Daus H, Bay W, Harig S, Schneider G, Feiden W, Schieffer H
Department of Internal Medicine I, University Hospital, Homburg/Saar, Germany.
Ann Hematol. 1998 Sep;77(3):139-41. doi: 10.1007/s002770050430.
Primary cardiac lymphoma is an extremely rare disease and is associated with a high mortality. In most cases, lymphomatous involvement of the heart and/or pericardium occurs as a late manifestation of disseminated disease. Primary cardiac lymphoma is treatable when appropriately diagnosed. We report the case of an immunocompetent 69-year-old patient who presented with signs of dyspnea and a transmural mass infiltrating the apical section of both ventricles. Examination of the tissue obtained by transvenous biopsy revealed high-grade non-Hodgkin's lymphoma of B-cell lineage. The patient was treated successfully with CHOP chemotherapy. This case demonstrates that early diagnosis and intensive chemotherapy might contribute to a better prognosis for patients with malignant lymphoma of the heart.
原发性心脏淋巴瘤是一种极为罕见的疾病，且死亡率很高。在大多数情况下，心脏和/或心包的淋巴瘤累及是播散性疾病的晚期表现。原发性心脏淋巴瘤若得到恰当诊断是可治疗的。我们报告一例69岁免疫功能正常的患者，该患者出现呼吸困难症状，且有一个透壁性肿块浸润双侧心室的心尖段。经静脉活检获取的组织检查显示为B细胞系高级别非霍奇金淋巴瘤。该患者接受CHOP化疗后成功治愈。此病例表明，早期诊断和强化化疗可能有助于改善心脏恶性淋巴瘤患者的预后。
