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经皮乙醇注射治疗不可切除胰腺癌——两例报告

[Percutaneous ethanol injection for unresectable pancreatic cancer-report of two cases].

作者信息

Yamamoto S, Miyake I, Takatori K, Ohmoto K, Mitsui Y, Shimabara M

机构信息

Division of Gastroenterology 1, Kawasaki Medical School.

出版信息

Gan To Kagaku Ryoho. 1998 Oct;25(12):1969-71.

PMID:9797822
Abstract

Two cases of unresectable pancreatic cancer underwent percutaneous ethanol injection (PEI). The first was a 65-year-old man with a 43 x 39 mm mass in the head of the pancreas. He received PEI (total 38.5 ml of ethanol) 6 times. Serum CA19-9 decreased from 3,800 U/ml to 1,700 U/ml. The patient was dead 6 months after PEI. Autopsy revealed coagulative necrosis at the site of ethanol injection. The second case was a 66-year-old man with a 70 x 50 mm mass in the body of the pancreas. He was treated by PEI (total 10 ml). After PEI, his abdominal pain was relieved considerably. He died 4 months after PEI treatment. These findings suggest that PEI may be useful not only for pain control but also for tumor reduction of unresectable pancreatic cancer.

摘要

两例无法切除的胰腺癌患者接受了经皮乙醇注射(PEI)治疗。第一例是一名65岁男性,胰腺头部有一个43×39毫米的肿块。他接受了6次PEI治疗(共注射乙醇38.5毫升)。血清CA19-9从3800 U/ml降至1700 U/ml。该患者在接受PEI治疗6个月后死亡。尸检显示乙醇注射部位出现凝固性坏死。第二例是一名66岁男性,胰腺体部有一个70×50毫米的肿块。他接受了PEI治疗(共10毫升)。PEI治疗后,他的腹痛得到了明显缓解。他在接受PEI治疗4个月后死亡。这些发现表明,PEI不仅可能有助于控制疼痛,还可能有助于缩小无法切除的胰腺癌的肿瘤。

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