Akiyama H, Kanzaki H, Tada J, Arata J
Department of Dermatology, Okayama University Medical School, Japan.
J Dermatol. 1998 Sep;25(9):563-8. doi: 10.1111/j.1346-8138.1998.tb02459.x.
We isolated 162 coagulase-negative staphylococci (48: from infection, 114: from colonization) from various skin diseases between January, 1995, and January, 1998. From eighteen infected cysts, 10 Staphylococcus epidermidis strains, 3 S. capitis strains, 2 S. hominis strains, 2 S. auricularis strains, and one S. saprophyticus strain were individually detected. Similarly, from ten folliculitis lesions, 6 S. epidermidis strains, 2 S. capitis strains, and 2 S. hominis strains, and from five furuncle lesions, 3 S. lugdunensis strains, one S. epidermidis strains, and one S. hominis strain were detected, respectively. Four abscesses with mild inflammatory signs were localized on the scalp; S. epidermidis strains alone were detected from them. From two felons, one S. lugdunensis strain and one S. haemolyticus strain were detected, respectively. Staphylococcus epidermidis and S. lugdunensis strains seems to be more frequently associated with skin suppurative lesions than other strains. Staphylococcus hominis strains and S. capitis strains were suggested to be potential pathogens in the initiation of suppuration in various purulent skin lesions. Among the 28 S. epidermidis strains, 13 (46.4%) were methicillin-resistant (oxacillin, minimum inhibitory concentration > or = 4 micrograms/ml). Twelve (29.3%) out of the other 41 coagulase-negative staphylococci were methicillin-resistant. Coagulase-positive and -negative staphylococci showed no differences in susceptibility tests against various antistaphylococcal agents.
1995年1月至1998年1月期间，我们从各种皮肤病中分离出162株凝固酶阴性葡萄球菌（48株来自感染，114株来自定植）。从18个感染囊肿中，分别检测到10株表皮葡萄球菌、3株头葡萄球菌、2株人葡萄球菌、2株耳葡萄球菌和1株腐生葡萄球菌。同样，从10个毛囊炎皮损中，检测到6株表皮葡萄球菌、2株头葡萄球菌和2株人葡萄球菌；从5个疖肿皮损中，分别检测到3株路邓葡萄球菌、1株表皮葡萄球菌和1株人葡萄球菌。4个有轻度炎症体征的脓肿位于头皮；从中仅检测到表皮葡萄球菌。从2个甲沟炎中，分别检测到1株路邓葡萄球菌和1株溶血葡萄球菌。表皮葡萄球菌和路邓葡萄球菌似乎比其他菌株更常与皮肤化脓性病变相关。人葡萄球菌和头葡萄球菌被认为是各种化脓性皮肤病变化脓起始的潜在病原体。在28株表皮葡萄球菌中，13株（46.4%）对甲氧西林耐药（苯唑西林，最低抑菌浓度≥4微克/毫升）。在其他41株凝固酶阴性葡萄球菌中，12株（29.3%）对甲氧西林耐药。凝固酶阳性和阴性葡萄球菌在针对各种抗葡萄球菌药物的药敏试验中无差异。
