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环境烟草烟雾与肺癌

Environmental tobacco smoke and lung cancer.

作者信息

Jöckel K H, Pohlabeln H, Ahrens W, Krauss M

机构信息

Institute for Medical Informatics, Biometry and Epidemiology, University Clinics of Essen, Germany.

出版信息

Epidemiology. 1998 Nov;9(6):672-5.

PMID:9799181
Abstract

In a case-control study of 1,004 lung cancer cases and 1,004 population controls, all nonsmokers (71 cases, 236 controls) were interviewed for their exposure to environmental tobacco smoke. On the basis of indices of duration, we separated intermediate and high exposures from low or no exposure. The odds ratio for high exposure was 2.09 (95% confidence interval = 1.02-4.28). Exposure from the spouse was only weakly associated with lung cancer risk. We found little association for exposure during childhood. High exposure at the work place showed an odds ratio of 1.91. There was little indication of confounding by dietary habits.

摘要

在一项针对1004例肺癌病例和1004名人群对照的病例对照研究中,对所有不吸烟者(71例病例,236名对照)就其接触环境烟草烟雾的情况进行了访谈。根据接触持续时间指标,我们将中度和高度接触与低度或无接触区分开来。高度接触的比值比为2.09(95%置信区间=1.02 - 4.28)。配偶造成的接触与肺癌风险仅呈弱关联。我们发现儿童期接触与肺癌风险几乎没有关联。工作场所的高度接触显示比值比为1.91。几乎没有迹象表明饮食习惯会造成混杂影响。

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