Reynolds P
Environmental Health Investigations Branch, California Department of Health Services, Oakland, California 94612, USA.
Environ Health Perspect. 1999 Dec;107 Suppl 6(Suppl 6):865-72. doi: 10.1289/ehp.99107s6865.
Exposure to environmental tobacco smoke (ETS) among individuals who have never smoked tobacco products has been well established as a risk factor for lung cancer. Most of the epidemiologic evidence for this association has come from studies of exposure to a spouse who smokes. Fewer studies have explicitly evaluated this risk relationship for workplace sources of ETS exposure. These are reviewed here in the context of study design issues and their contributions to the overall evidence for risks of ETS exposure in the workplace. Although most studies have low power to detect workplace risk estimates in the modest range suggested by the larger studies, risk estimates tend to be consistent with those for exposure from a smoking spouse.
对于从未吸食烟草制品的个体而言,接触环境烟草烟雾(ETS)已被充分确认为肺癌的一个风险因素。这种关联的大多数流行病学证据来自对接触吸烟配偶的研究。较少有研究明确评估工作场所ETS接触源的这种风险关系。在此,我们结合研究设计问题及其对工作场所ETS接触风险总体证据的贡献来对此进行综述。尽管大多数研究检测工作场所风险估计值的能力较低,而这些估计值处于大型研究提出的适度范围内,但风险估计值往往与接触吸烟配偶的风险估计值一致。