Clarke L P, Maugham E Z, Laughlin J S, Knapper W H, Mayer K
Med Phys. 1976;3(5):324-7. doi: 10.1118/1.594288.
Conventional methods for measuring splenic sequestration of labeled cells rely on stationary probe counting over the liver and spleen. A quantitative spleen-scanning method is proposed as a means of performing a more accurate diagnosis of the degree of splenic sequestration. Improved methods for calibrating a rectilinear scanner employing "constant resolutions" collimators, designed for the in vivo measurement, are reported, Clinical evaluation of this method was performed by scanning several patients scheduled for splenectomy. Good correlation between in vivo and in vitro measurements of splenic radioactivity for 29 patients was obtained. A least-squares fit to the data yielded a coefficient of determination r2=0.93.
测量标记细胞脾脏潴留的传统方法依赖于对肝脏和脾脏进行固定探头计数。本文提出一种定量脾脏扫描方法，作为更准确诊断脾脏潴留程度的手段。报告了改进的校准采用“恒定分辨率”准直器的直线扫描仪的方法，该准直器专为体内测量而设计。通过对几名计划进行脾切除术的患者进行扫描，对该方法进行了临床评估。获得了29例患者脾脏放射性的体内和体外测量值之间的良好相关性。对数据进行最小二乘拟合得到决定系数r2 = 0.93。
