Diffley J F
ICRF Clare Hall Laboratories South Mimms, Hertfordshire, EN6 3LD, UK.
Curr Biol. 1998 Oct 22;8(21):R771-3. doi: 10.1016/s0960-9822(07)00483-6.
Budding yeast replication origins are activated during S phase according to a predetermined temporal programme. Two recent studies indicate that this programme is executed, at least in part, by the S-phase-promoting cyclins that act to assemble a pre-initiation complex which includes the Cdc45 protein.
出芽酵母的复制起点会在S期按照预定的时间程序被激活。最近的两项研究表明,该程序至少部分是由促进S期的细胞周期蛋白执行的,这些细胞周期蛋白作用于组装一个包括Cdc45蛋白的预起始复合物。