John T J, Samuel R, Balraj V, John R
Department of Clinical Virology, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Lancet. 1998 Jul 4;352(9121):58-61. doi: 10.1016/s0140-6736(97)10494-9.
For over a decade we have maintained within a district of 5 million people, a system of prompt reporting of cases of childhood vaccine-preventable diseases, encephalitis, meningitis, hepatitis, and rabies; together with a sentinel laboratory surveillance of cholera, typhoid fever, malaria, HIV infection and antimicrobial-resistance patterns of selected pathogens. The system combined government and private sectors, with every hospital enrolled and participating. Reports were scanned daily on a computer for any clustering of cases. Interventions included investigations, immunisation, antimicrobial treatment, health education, and physical rehabilitation of children with paralysis. All vaccine-preventable diseases have declined markedly, whilst malaria and HIV infections have increased steadily. Annual expense was less than one US cent per head. The reasons for the success and sustainability of this model include simplicity or reporting procedure, low budget, private-sector participation, personal rapport with people in the network, regular feedback of information through a monthly bulletin, and the visible interventions consequent upon reporting. This district-level disease surveillance model is replicable in developing countries for evaluating polio eradication efforts, monitoring immunisation programmes, detecting outbreaks of old or new diseases, and for evaluating control measures.
十多年来,我们在一个拥有500万人口的地区维持了一个系统,用于及时报告儿童疫苗可预防疾病、脑炎、脑膜炎、肝炎和狂犬病病例;同时对霍乱、伤寒、疟疾、艾滋病毒感染以及选定病原体的抗菌药物耐药模式进行哨点实验室监测。该系统整合了政府和私营部门,每家医院都参与其中。每天在计算机上扫描报告,查看是否有病例聚集情况。干预措施包括调查、免疫接种、抗菌治疗、健康教育以及对瘫痪儿童的身体康复。所有疫苗可预防疾病都显著下降,而疟疾和艾滋病毒感染则稳步增加。每年的费用人均不到一美分。该模式取得成功并得以持续的原因包括报告程序简单、预算低、私营部门参与、与网络中的人员建立个人关系、通过月度公报定期反馈信息以及报告后采取的可见干预措施。这种区级疾病监测模式在发展中国家可用于评估脊髓灰质炎根除工作、监测免疫规划、检测新旧疾病的暴发以及评估控制措施。