Krausz M, Degkwitz P, Kühne A, Verthein U
Klinik für Psychiatrie und Psychotherapie, der Universität Hamburg (UKE), Germany.
Addict Behav. 1998 Nov-Dec;23(6):767-83. doi: 10.1016/s0306-4603(98)00099-9.
In a 5-year-follow-up study of 350 opiate addicts in contact with a drug help system in Hamburg, 272 clients (78%) were interviewed a second time after 1 year. The objective of the study was to examine the correlation between mental disorders and drug consumption and its relationship to clients' general life situation. In the majority of the opiate addicts, a pattern of polydrug consumption was observed, but the amount of drugs consumed was clearly lower after 1 year. In the initial survey, a mental disorder according to ICD-10 could be diagnosed for 55% of the sample. Among groups formed by the severity and course of mental disorders or their symptoms, a significant correlation was observed, particularly at the time of follow-up, between the extent of drug consumption and the course of the mental disorder. Other areas, like physical health or social problems/conflicts, were also related to comorbidity (i.e., heavy drug consumption and/or mental disorder). These interrelationships should be taken into account in treatment, care and guidance to increase the prospects for successful treatment.
在一项针对汉堡一个毒品救助系统中350名阿片类药物成瘾者的5年随访研究中，1年后对272名服务对象（78%）进行了第二次访谈。该研究的目的是检验精神障碍与药物消费之间的相关性及其与服务对象总体生活状况的关系。在大多数阿片类药物成瘾者中，观察到了多药滥用模式，但1年后药物消费量明显降低。在初次调查中，根据国际疾病分类第10版，55%的样本可诊断出精神障碍。在根据精神障碍的严重程度、病程或其症状形成的组中，观察到药物消费程度与精神障碍病程之间存在显著相关性，尤其是在随访时。其他领域，如身体健康或社会问题/冲突，也与共病（即大量药物消费和/或精神障碍）有关。在治疗、护理和指导中应考虑这些相互关系，以提高成功治疗的前景。
