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关于创伤后应激障碍(PTSD)与酒精滥用之间关系的流行病学证据:关联的本质。

Epidemiological evidence about the relationship between PTSD and alcohol abuse: the nature of the association.

作者信息

McFarlane A C

机构信息

University of Adelaide, Department of Psychiatry, Queen Elizabeth Hospital, Woodville, Australia.

出版信息

Addict Behav. 1998 Nov-Dec;23(6):813-25. doi: 10.1016/s0306-4603(98)00098-7.

Abstract

This article uses the Bradford Hill criteria for assessing causal associations to examine the nature of the relationship between PTSD and alcohol abuse. A series of studies are presented which examine this relationship. A cross-sectional study of 2,501 subjects in a community sample examined the relationship between at-risk drinking and 11 types of traumatic events. The traumatic events associated with at-risk drinking were involvement in life threatening accidents, witnessing severe injury, rape, being the victim of serious physical assault using the CIDI. In a longitudinal study of 469 firefighters exposed to a natural disaster, PTSD was associated with both an increase and decrease in alcohol consumption and PTSD rather than exposure accounted for the changes in drinking behaviour. In three other populations, psychiatric inpatients, motor accident victims and female prisoners, the association between PTSD and alcohol abuse emphasised the clinical and public health importance of this relationship. The available evidence does nevertheless support the causal nature of this relationship. Other risk factors are necessary to predict alcohol abuse following exposure to traumatic events, although exposure to traumatic events can be caused by alcohol abuse.

摘要

本文采用布拉德福德·希尔标准来评估因果关联,以研究创伤后应激障碍(PTSD)与酒精滥用之间关系的本质。文中呈现了一系列研究这一关系的内容。一项针对社区样本中2501名受试者的横断面研究,考察了高危饮酒与11种创伤事件之间的关系。与高危饮酒相关的创伤事件包括遭遇危及生命的事故、目睹重伤、强奸以及使用复合性国际诊断交谈检查表(CIDI)确定为严重身体攻击的受害者。在一项对469名经历自然灾害的消防员的纵向研究中,PTSD与酒精摄入量的增加和减少均有关联,且是PTSD而非暴露因素导致了饮酒行为的变化。在其他三类人群,即精神科住院患者、交通事故受害者和女性囚犯中,PTSD与酒精滥用之间的关联凸显了这种关系在临床和公共卫生方面的重要性。然而现有证据确实支持这种关系的因果本质。尽管创伤事件暴露可能由酒精滥用引起,但要预测创伤事件暴露后是否会出现酒精滥用,还需要考虑其他风险因素。

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