Robitaille P M, Abduljalil A M, Kangarlu A, Zhang X, Yu Y, Burgess R, Bair S, Noa P, Yang L, Zhu H, Palmer B, Jiang Z, Chakeres D M, Spigos D
Department of Radiology, The Ohio State University, Columbus 43210, USA.
NMR Biomed. 1998 Oct;11(6):263-5. doi: 10.1002/(sici)1099-1492(199810)11:6<263::aid-nbm549>3.0.co;2-0.
In this work, we present the first human magnetic resonance image (MRI) obtained at ultrahigh field strengths (8 T). We demonstrate that clinical imaging will be possible at 8 T and that reasonable quality head images can be obtained at this field strength. Most importantly, we emphasize that the power required to excite the spins at 8 T is much lower than had previously been predicted by the nuclear magnetic resonance theory. A 90 degree pulse in the head at 8 T requires only approximately 0.085 J of energy (90 W for a 2-lobe 4 ms sinc pulse). Based on measurements at 4 T, 1-2 J of energy should have been utilized to achieve a 90 degree excitation at 8 T. The fact that the energy required for spin excitation at 8 T is much lower than predicted by the NMR theory, will be extremely important to the viability of ultrahigh field imaging, since concerns related to power absorption and specific absorption rate (SAR) violations at ultrahigh field are alleviated. As such, it will be possible to utilize RF intensive pulse sequences and adiabatic spin excitation at 8 T without significant risk to the subject.
在这项工作中,我们展示了在超高场强(8T)下获得的首张人体磁共振成像(MRI)。我们证明了在8T下进行临床成像是可行的,并且在该场强下能够获得质量合理的头部图像。最重要的是,我们强调在8T下激发自旋所需的功率远低于此前核磁共振理论的预测。在8T下对头部施加一个90度脉冲仅需约0.085焦耳的能量(对于一个两叶4毫秒的辛格脉冲为90瓦)。基于在4T下的测量,在8T下实现90度激发本应需要1 - 2焦耳的能量。8T下自旋激发所需能量远低于核磁共振理论预测这一事实,对于超高场成像的可行性极为重要,因为与超高场下功率吸收和比吸收率(SAR)违规相关的担忧得到了缓解。因此,在8T下使用射频密集脉冲序列和绝热自旋激发对受试者不会有显著风险。