Jato M, Rubio F
Servicio de Neurología, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Ll., Barcelona, España.
Rev Neurol. 1998 Oct;27(158):667-71.
Purely bulbar hematomas are not common (0.25%-0.50% of all intraparenchymatous hematomas), probably because of the particular characteristics of the anatomy and hemodynamics of the bulbar circulation.
We selected 18 cases. Three of these were our own and the purely bulbar localization was confirmed by neuroimaging surgical findings and necropsy. Its appearance was related to arterial hypertension, anticoagulant treatment and obvious or occult vascular malformations, although in a considerable proportion (39%) no cause was found. Although arterial hypertension is less important in its etiopathogenesis as compared with other sites of intraparenchymatous hemorrhage, 7 of the patients were hypertensive. The commonest clinical findings were nystagmus (72%), and dysphagia and hypoglossal paralysis (61%). The commonest site was posterior. Arteriography was of little use since this was normal in all the cases in which it was done (72%). The presence of angiographically occult malformations made it advisable to use magnetic resonance and repeat this after the acute phase. Three quarters of the patients were treated medically. Mortality (22%) was lower than the overall rate for posterior fossa hematomas, and the prognosis was better since no survivors had incapacitating sequelae.
The specific etiopathogeneses, clinical characteristics and course of bulbar hematomas makes it advisable to do a differential study regarding other types of intracerebral hemorrhage.
单纯延髓血肿并不常见(占所有脑实质内血肿的0.25%-0.50%),这可能是由于延髓循环的解剖结构和血流动力学的特殊特点所致。
我们选取了18例病例。其中3例为我们自己的病例,其单纯延髓定位通过神经影像学、手术发现及尸检得以证实。其出现与动脉高血压、抗凝治疗以及明显或隐匿的血管畸形有关,尽管相当一部分(39%)病例未发现病因。与其他脑实质内出血部位相比,动脉高血压在其发病机制中的重要性较低,但7例患者患有高血压。最常见的临床表现为眼球震颤(72%),以及吞咽困难和舌下神经麻痹(61%)。最常见的部位是后部。血管造影检查作用不大,因为在所有进行该项检查的病例(72%)中结果均正常。存在血管造影隐匿性畸形使得建议使用磁共振成像,并在急性期后重复检查。四分之三的患者接受了药物治疗。死亡率(22%)低于后颅窝血肿的总体死亡率,且预后较好,因为幸存者均无致残性后遗症。
延髓血肿的特定发病机制、临床特征及病程使得有必要针对其他类型的脑出血进行鉴别研究。