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美沙酮治疗患者中可卡因戒断强化的广泛有益效果。

Broad beneficial effects of cocaine abstinence reinforcement among methadone patients.

作者信息

Silverman K, Wong C J, Umbricht-Schneiter A, Montoya I D, Schuster C R, Preston K L

机构信息

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

J Consult Clin Psychol. 1998 Oct;66(5):811-24. doi: 10.1037//0022-006x.66.5.811.

Abstract

Escalating reinforcement for sustained abstinence has been effective in treating cocaine abuse. Under this schedule, patients receive vouchers for cocaine-free urine samples; vouchers have monetary values that increase with the number of consecutive cocaine-free urine samples. Cocaine-abusing methadone patients were randomly assigned to receive vouchers for 12 weeks under (a) an escalating schedule (n = 20), (b) an escalating schedule with start-up bonuses (n = 20), or (c) a noncontingent schedule (n = 19). Start-up bonuses were designed to provide added reinforcement for initiating abstinence; however, they did not improve outcomes. Both contingent interventions significantly increased cocaine abstinence. In addition, the contingent interventions increased abstinence from opiates and decreased reports of cocaine craving. These results replicate the efficacy of cocaine abstinence reinforcement and show that it can have broad beneficial effects.

摘要

逐步加强对持续戒除可卡因的强化措施在治疗可卡因滥用方面已取得成效。按照这一方案,患者若提供不含可卡因的尿液样本便可获得代金券;代金券的货币价值会随着连续不含可卡因尿液样本的数量增加而提高。滥用可卡因的美沙酮患者被随机分配,在以下三种情况下接受为期12周的代金券:(a) 逐步递增方案(n = 20),(b) 有启动奖金的逐步递增方案(n = 20),或 (c) 非条件方案(n = 19)。启动奖金旨在为开始戒除提供额外强化;然而,它们并未改善治疗效果。两种条件性干预措施均显著提高了可卡因戒除率。此外,条件性干预措施增加了阿片类药物的戒除率,并减少了对可卡因渴望的报告。这些结果重复了可卡因戒除强化措施的疗效,并表明它可产生广泛的有益影响。

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