Triantafyllou A, Harrison J D
Oral Pathology Laboratory, Liverpool University Dental Hospital and School of Dentistry, England.
Ultrastruct Pathol. 1998 Jul-Aug;22(4):305-7. doi: 10.3109/01913129809103351.
Foci of calcification were found ultrastructurally in the wall of an arteriole of a specimen of chronic submandibular sialadenitis. They were seen in the basement membrane surrounding the smooth muscle cells, where some of them were associated with vesicles and membraneous debris, and in a macrophage. Calcium and phosphorus were detected microanalytically in the calcifications, which contained needle-shaped crystals. The calcifications in the basement membrane may have started in vesicles released from smooth muscle cells and those in the macrophage may have arisen by heterophagy. Matrix vesicles appear to be of significance in arteriolar calcification and macrophages may offer protection against it.
在慢性颌下腺涎腺炎标本的一条小动脉壁中,通过超微结构发现了钙化灶。在围绕平滑肌细胞的基底膜中可见钙化灶,其中一些与囊泡和膜性碎片相关,并且在巨噬细胞中也有发现。通过微量分析在钙化灶中检测到了钙和磷,钙化灶中含有针状晶体。基底膜中的钙化可能起始于平滑肌细胞释放的囊泡,而巨噬细胞中的钙化可能是通过异体吞噬形成的。基质囊泡似乎在小动脉钙化中具有重要意义,而巨噬细胞可能对其起到保护作用。