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比较机制与条件性抑制:条件刺激预暴露会破坏巴甫洛夫条件性抑制,但不会破坏明确的非配对抑制。

Comparator mechanisms and conditioned inhibition: conditioned stimulus preexposure disrupts Pavlovian conditioned inhibition but not explicitly unpaired inhibition.

作者信息

Friedman B X, Blaisdell A P, Escobar M, Miller R R

机构信息

Department of Psychology, State University of New York at Binghamton 13902-6000, USA.

出版信息

J Exp Psychol Anim Behav Process. 1998 Oct;24(4):453-66.

PMID:9805791
Abstract

Three conditioned lick-suppression experiments with rats examined the effects of pretraining exposure to the conditioned stimulus (CS) on behavior indicative of conditioned inhibition. After CS-preexposure treatment, subjects received either Pavlovian conditioned inhibition training or explicitly unpaired inhibition training with the preexposed CS. The inhibitory status of the CS was then assessed with a retardation (Experiment 1) or a summation (Experiment 2) test. Experiment 3 controlled for the unconditioned stimulus-preexposure effect being a potential confound in Experiments 1 and 2. As predicted by the comparator hypothesis (R. R. Miller & L. D. Matzel, 1988), the CS-context association that developed during the CS-preexposure phase disrupted the expression of Pavlovian conditioned inhibition but not the expression of explicitly unpaired inhibition.

摘要

三项针对大鼠的条件性舔舐抑制实验,研究了预训练暴露于条件刺激(CS)对指示条件性抑制行为的影响。在CS预暴露处理后,实验对象接受了巴甫洛夫条件性抑制训练,或使用预暴露的CS进行明确的非配对抑制训练。然后通过延迟(实验1)或总和(实验2)测试来评估CS的抑制状态。实验3控制了非条件刺激预暴露效应,这在实验1和实验2中可能是一个潜在的混淆因素。正如比较器假说(R. R. 米勒和L. D. 马泽尔,1988年)所预测的那样,在CS预暴露阶段形成的CS-情境关联破坏了巴甫洛夫条件性抑制的表达,但没有破坏明确非配对抑制的表达。

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