Moody A R, Pollock J G, O'Connor A R, Bagnall M
Department of Academic Radiology, University Hospital, Queen's Medical Centre, Nottingham, England.
Radiology. 1998 Nov;209(2):349-55. doi: 10.1148/radiology.209.2.9807558.
To determine the feasibility of diagnosing deep venous thrombosis (DVT) with direct three-dimensional magnetic resonance (MR) imaging of the thrombus.
Eighteen patients with proved DVT at conventional venography were evaluated with a magnetization-prepared three-dimensional blood- and fat-suppressed MR imaging sequence. The presence and extent of thrombosis on the MR images were compared with the findings at conventional venography.
At MR imaging, DVT was visualized in 17 of the 18 patients. MR imaging demonstrated greater proximal extent of the thrombosis in four patients, asymptomatic contralateral thrombosis in one, involvement of the deep femoral vein in five, and involvement of the superficial venous system in three.
Direct MR imaging of clots appears capable of demonstrating venographically diagnosed DVT. This MR imaging technique is noninvasive, quick, and repeatable and allows a survey of the whole lower-limb venous system. Detection of thrombosis relies on the formation of methemoglobin, which appears to be sufficiently rapid to allow use of this technique in the clinical setting. Changes in the signal from clot over time may allow estimation of the age of the thrombus.
确定通过对血栓进行直接三维磁共振（MR）成像来诊断深静脉血栓形成（DVT）的可行性。
对18例经传统静脉造影证实患有DVT的患者，采用磁化准备的三维血液和脂肪抑制MR成像序列进行评估。将MR图像上血栓的存在情况及范围与传统静脉造影的结果进行比较。
在MR成像中，18例患者中有17例显示出DVT。MR成像显示4例患者血栓近端范围更大，1例有无症状的对侧血栓形成，5例累及股深静脉，3例累及浅静脉系统。
对血栓进行直接MR成像似乎能够显示经静脉造影诊断的DVT。这种MR成像技术是非侵入性的、快速的且可重复的，并且能够对整个下肢静脉系统进行检查。血栓的检测依赖于高铁血红蛋白的形成，其形成速度似乎足够快，使得该技术能够在临床环境中应用。随着时间推移，血栓信号的变化可能有助于估计血栓的形成时间。
