Claudel P, Labbé L, Pedespan J M, Labrèze C, Taïeb A
Unité de dermatologie pédiatrique, hôpital Pellegrin-Enfants, Bordeaux, France.
Arch Pediatr. 1998 Oct;5(10):1098-102. doi: 10.1016/s0929-693x(99)80007-4.
Two cases of linear and whorled nevoid hypermelanosis are reported. Cutaneous lesions (hyperpigmented macules along Blaschko's lines) appeared gradually after birth. Neurologic anomalies were detected in both cases (symptomatic in one, only cerebral MRI anomalies in the other).
This sporadic condition, probably caused by somatic mosaicism, must be differentiated from incontinentia pigmenti, Mac Cune-Albright disease and chimerism. Its situation among the Blaschko linear pigmentary anomalies (hypomelanosis of Ito) is discussed.
报告了两例线状和涡状痣样色素沉着过度病例。皮肤损害（沿布拉斯科线的色素沉着斑）在出生后逐渐出现。两例均检测到神经学异常（一例有症状，另一例仅脑磁共振成像有异常）。
这种散发性疾病可能由体细胞镶嵌现象引起，必须与色素失禁症、麦库恩-奥尔布赖特病和嵌合体相鉴别。文中讨论了其在布拉斯科线状色素异常（伊藤色素减退症）中的情况。
