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使酒精成瘾治疗方法与个体差异相匹配:治疗的主要效果及治疗期间匹配对饮酒的影响。匹配项目研究小组

Matching alcoholism treatments to client heterogeneity: treatment main effects and matching effects on drinking during treatment. Project MATCH Research Group.

出版信息

J Stud Alcohol. 1998 Nov;59(6):631-9. doi: 10.15288/jsa.1998.59.631.

DOI:10.15288/jsa.1998.59.631
PMID:9811084
Abstract

OBJECTIVE

This article examines client drinking and related psychosocial functioning during the course of alcoholism treatment. It focuses on (1) the main effects of the three Project MATCH treatments, (2) the prognostic value of client attributes employed in the matching hypotheses, and (3) the attribute by treatment interaction effects.

METHOD

Clients recruited from outpatient settings (n = 952) or from aftercare settings (n = 774) were randomized to one of the following treatments: Motivational Enhancement Therapy (MET), Cognitive Behavioral Therapy (CBT) and Twelve-Step Facilitation (TSF). Alcohol consumption and psychosocial functioning during treatment were assessed at the end of the 12-week treatment phase.

RESULTS

During the treatment phase, small but statistically significant differences among treatments were found only in the outpatient arm on measures of alcohol consumption and alcohol-related negative consequences. Forty-one percent (41%) of CBT and TSF clients were abstinent or drank moderately without alcohol-related consequences, compared with 28% of MET clients. Tests of 10 a priori primary client-treatment matching hypotheses failed to find any interaction effects that had an impact on drinking throughout the treatment phase.

CONCLUSIONS

In the outpatient setting there appears to be a temporary advantage to assigning individuals to CBT or TSF rather than MET. When there is a need to quickly reduce heavy drinking and alcohol-related consequences, it appears that CBT or TSF should be the treatment of choice.

摘要

目的

本文探讨酒精成瘾治疗过程中患者的饮酒情况及相关心理社会功能。重点关注:(1)三种匹配项目治疗的主要效果;(2)匹配假设中所采用的患者属性的预后价值;(3)属性与治疗的交互作用效果。

方法

从门诊患者(n = 952)或后续护理机构(n = 774)招募的患者被随机分配到以下治疗之一:动机增强疗法(MET)、认知行为疗法(CBT)和十二步促进疗法(TSF)。在12周治疗阶段结束时评估治疗期间的饮酒量和心理社会功能。

结果

在治疗阶段,仅在门诊患者组中发现治疗之间在饮酒量和与酒精相关的负面后果测量上存在微小但具有统计学意义的差异。41%的接受CBT和TSF治疗的患者戒酒或适度饮酒且无酒精相关后果,而接受MET治疗的患者这一比例为28%。对10个先验的主要患者-治疗匹配假设进行的测试未发现任何在整个治疗阶段对饮酒有影响的交互作用效果。

结论

在门诊环境中,将个体分配到CBT或TSF而非MET似乎有暂时的优势。当需要快速减少大量饮酒和与酒精相关的后果时,CBT或TSF似乎应作为首选治疗方法。

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