Barker G J
NMR Research Unit, Institute of Neurology, London, UK.
Magn Reson Imaging. 1998 Sep;16(7):715-20. doi: 10.1016/s0730-725x(98)00084-8.
Since its introduction, the fluid attenuated inversion recovery (FLAIR) sequence has found many applications in the central nervous system (CNS), because of its heavy T2 weighting and excellent cerebrospinal fluid (CSF) suppression. More recently fast spin-echo based variants have been developed that greatly reduce scan time; such sequences are often referred to as "fast FLAIR." We present what we believe to be the first implementation of FLAIR using a three dimensional (3D) fast spin-echo-based pulse sequence, which combines the cerebrospinal fluid suppression and good lesion contrast of two-dimensional fast FLAIR with the advantages of a three-dimensional sequence such as higher signal-to-noise ratio (SNR) per unit time, thinner slices (giving reduced partial volume effect) and the ability to reformat the data in an arbitrary plane.
自液体衰减反转恢复（FLAIR）序列问世以来，因其具有重T2加权和出色的脑脊液（CSF）抑制效果，已在中枢神经系统（CNS）中得到广泛应用。最近，基于快速自旋回波的变体技术得以开发，大幅缩短了扫描时间；此类序列通常被称为“快速FLAIR”。我们展示了我们认为的首次使用基于三维（3D）快速自旋回波脉冲序列实现的FLAIR，该序列将二维快速FLAIR的脑脊液抑制和良好的病变对比度与三维序列的优势相结合，如单位时间内更高的信噪比（SNR）、更薄的层面（减少部分容积效应）以及能够在任意平面上重新格式化数据。
