南美蟛蜞菊不同部位的植物化学与药理学分析（菊科）

Phytochemical and pharmacological analysis of different parts of Wedelia paludosa DC. (Compositae).

作者信息

Block L C, Scheidt C, Quintão N L, Santos A R, Cechinel-Filho V

机构信息

Químico-Farmacêuticas (NIQFAR)/CCS, Universidade do Vale do Itajaí (UNIVALI), Itajaí, SC, Brazil.

出版信息

Pharmazie. 1998 Oct;53(10):716-8.

PMID:9812340

Abstract

This study demonstrates the chromatographic profile and antinociceptive action of methanolic extracts obtained from different parts of Wedelia paludosa, a medicinal plant employed in folk medicine to treat dolorous processes. The results indicated that the root was the most potent part whereas the flower exhibited a weak antinociceptive activity. Comparative TLC suggested that all extract show different constituents or concentrations. Kaurenoic acid and stigmasterol were detected in all extracts and luteolin is present only in leaves and stems, but in small quantities. These results confirm our previous investigation on this plant and support its popular use for the treatment of algesic processes.

摘要

本研究展示了从南美蟛蜞菊不同部位获得的甲醇提取物的色谱图谱和镇痛作用。南美蟛蜞菊是一种民间医学中用于治疗疼痛病症的药用植物。结果表明，根部是最有效的部位，而花表现出较弱的镇痛活性。比较薄层层析表明，所有提取物显示出不同的成分或浓度。在所有提取物中均检测到贝壳杉烯酸和豆甾醇，而木犀草素仅存在于叶和茎中，但含量较少。这些结果证实了我们之前对该植物的研究，并支持其在治疗疼痛病症方面的广泛应用。