Rahim F, Rehman F, Ahmad S, Zada B
DHQ Hospital, Timergara, N.W.F.P.
J Pak Med Assoc. 1998 Jun;48(6):161-2.
Visceral leishmaniasis is endemic in District Dir, NWFP. We evaluated 10 patients with visceral leishmaniasis at DHQ Hospital Timergara District Dir, N.W.F.P. All patients were in the age range 2 to 10 years. The predominant clinical features in these were chronic fever (10), splenomegaly (10), hepatomegaly (10), weight loss (10) and abdominal distention (5). Lymphadenopathy was absent. Common laboratory abnormalities included anaemia (10), leucopenia (7), thrombocytopenia (10) and hypergammaglobulinaemia (10). Formal Gel test was positive in all patients (100%) and all had positive bone marrow smears for Leishmania Donovani (L.D.) bodies (10). The response to stibogluconate (Glucantime Sodium) therapy was good with a 100 percent cure rate.
内脏利什曼病在西北边境省迪尔地区呈地方流行。我们在西北边境省迪尔地区蒂默加拉市的DHQ医院对10例内脏利什曼病患者进行了评估。所有患者年龄在2至10岁之间。这些患者的主要临床特征为长期发热（10例）、脾肿大（10例）、肝肿大（10例）、体重减轻（10例）和腹胀（5例）。无淋巴结病。常见的实验室异常包括贫血（10例）、白细胞减少（7例）、血小板减少（10例）和高球蛋白血症（10例）。所有患者的福尔马林凝胶试验均为阳性（100%），且所有患者的骨髓涂片利杜体均呈阳性（10例）。对葡萄糖酸锑钠（葡糖胺锑钠）治疗的反应良好，治愈率达100%。
