August C, Hustert B
Institut für Pathologie, Westfälischen Wilhelms-Universität Münster.
Pathologe. 1998 Sep;19(5):384-7. doi: 10.1007/s002920050302.
Histologic, immunohistochemical and ultrastructural results of a rhinoscleroma diagnosed bioptically on a 38 aged man are demonstrated. The characteristic light microscopic sign is a plasmocytic inflammatory infiltrate with dense packed foamy transformed macrophages (Mikulicz cells) ultrastructurally containing diplobacilli (Klebsiella rhinoscleromatis, gram negative agent of the lesion). The lesion has to be differentiated as of other inflammatory diseases as of plasmocytoma. A local application of acriflavin solution 2% was of therapeutical benefit.
展示了一名38岁男性经活检诊断为鼻硬结病的组织学、免疫组织化学和超微结构结果。特征性的光镜表现是浆细胞性炎症浸润，伴有密集排列的泡沫状转化巨噬细胞（米库利奇细胞），超微结构显示其含有双杆菌（鼻硬结克雷伯菌，该病变的革兰氏阴性病原体）。该病变必须与其他炎症性疾病以及浆细胞瘤相鉴别。局部应用2%的吖啶黄素溶液具有治疗效果。
