Harik-Khan R I, Wise R A, Fozard J L
Laboratory of Clinical Investigation, National Institute on Aging, Gerontology Research Center, Baltimore, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Am J Respir Crit Care Med. 1998 Nov;158(5 Pt 1):1459-64. doi: 10.1164/ajrccm.158.5.9712006.
A variety of methods for subject selection and test procedures have been used for the determination of normal values and reference equations for maximal inspiratory pressure (MIP). In the cross-sectional study described here, we made MIP measurements on 668 men and women in the Baltimore Longitudinal Study of Aging (BLSA), using a standardized electronic procedure. Results were combined with spirometric and anthropometric measurements. After subjecting them to rigorous health screening, we analyzed a well-defined, healthy subgroup of 139 men and 128 women with a wide age range (20 to 90 yr), using multiple linear regression, for the purpose of determining the effect of age, other correlates, normal values, and gender-specific reference equations for MIP. The gender effect was strong, with the average MIP values of the men being about 30% higher than those of the women (101 cm H2O and 72 cm H2O, respectively). The reference equation for men is: MIP +/- standard error of the estimate (SEE) = 126 - 1.028 x age + 0.343 x weight (kg) +/- (22.4); and for women: MIP +/- SEE = 171 - 0.694 x age + 0. 861 x weight (kg) - 0.743 x height (cm) +/- (18.5). These equations may be used for the assessment of inspiratory muscle strength.
为了确定最大吸气压（MIP）的正常值和参考方程，人们采用了多种受试者选择方法和测试程序。在本横断面研究中，我们使用标准化电子程序，对巴尔的摩纵向衰老研究（BLSA）中的668名男性和女性进行了MIP测量。结果与肺活量测定和人体测量数据相结合。在对他们进行严格的健康筛查后，我们使用多元线性回归分析了一个明确界定的健康亚组，该亚组包括139名男性和128名女性，年龄范围广泛（20至90岁），目的是确定年龄、其他相关因素、正常值以及MIP的性别特异性参考方程的影响。性别效应显著，男性的平均MIP值比女性高约30%（分别为101 cm H2O和72 cm H2O）。男性的参考方程为：MIP±估计标准误差（SEE）= 126 - 1.028×年龄 + 0.343×体重（kg）±（22.4）；女性的参考方程为：MIP±SEE = 171 - 0.694×年龄 + 0.861×体重（kg） - 0.743×身高（cm）±（18.5）。这些方程可用于评估吸气肌力量。
