22型脑膜炎奈瑟菌中PorB蛋白的异质性
Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis.
作者信息
Urwin R, Fox A J, Musilek M, Kriz P, Maiden M C
机构信息
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom.
出版信息
J Clin Microbiol. 1998 Dec;36(12):3680-2. doi: 10.1128/JCM.36.12.3680-3682.1998.
Abstract
The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.
摘要
通过基因测序研究了被鉴定为22血清型的脑膜炎球菌分离株中porB基因的遗传多样性。该程序鉴定出7种不同的porB序列，表明22血清型单克隆抗体识别的PorB蛋白存在变异。这与先前报道的22血清型脑膜炎球菌的遗传异质性一致。
相似文献
1
Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis.22型脑膜炎奈瑟菌中PorB蛋白的异质性
J Clin Microbiol. 1998 Dec;36(12):3680-2. doi: 10.1128/JCM.36.12.3680-3682.1998.
2
Correlation between serological and sequencing analyses of the PorB outer membrane protein in the Neisseria meningitidis serotyping system.脑膜炎奈瑟菌血清分型系统中PorB外膜蛋白的血清学分析与测序分析之间的相关性
Clin Diagn Lab Immunol. 1998 May;5(3):348-54. doi: 10.1128/CDLI.5.3.348-354.1998.
3
Genetic and immunologic characterization of a novel serotype 4, 15 strain of Neisseria meningitidis.新型4,15血清型脑膜炎奈瑟菌菌株的遗传学和免疫学特征
FEMS Immunol Med Microbiol. 2000 Nov;29(3):169-76. doi: 10.1111/j.1574-695X.2000.tb01519.x.
4
Sequencing of the porB gene: a step toward a true characterization of Neisseria meningitidis.脑膜炎奈瑟菌porB基因测序：迈向脑膜炎奈瑟菌真正特征描述的一步。
Clin Vaccine Immunol. 2006 Oct;13(10):1087-91. doi: 10.1128/CVI.00211-06.
5
Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains.B群：4型脑膜炎奈瑟菌菌株之间的遗传关系。
Rev Inst Med Trop Sao Paulo. 2001 May-Jun;43(3):119-24. doi: 10.1590/s0036-46652001000300001.
6
Vaccine-induced IgG antibodies to the linear epitope on the PorB outer membrane protein promote opsonophagocytosis of Neisseria meningitidis by human neutrophils.疫苗诱导产生的针对PorB外膜蛋白线性表位的IgG抗体可促进人类中性粒细胞对脑膜炎奈瑟菌的调理吞噬作用。
Clin Immunol Immunopathol. 1997 Jul;84(1):27-35. doi: 10.1006/clin.1997.4360.
7
Molecular variation of meningococcal serotype 4 antigen genes.脑膜炎球菌4型血清型抗原基因的分子变异
Epidemiol Infect. 1998 Aug;121(1):95-101. doi: 10.1017/s0950268898008942.
8
Amplification of the meningococcal porB gene for non-culture serotype characterization.用于非培养血清型鉴定的脑膜炎球菌porB基因扩增
Epidemiol Infect. 1998 Jun;120(3):257-62. doi: 10.1017/s0950268898008656.
9
Heterogeneity in non-epitope loop sequence and outer membrane protein complexes alters antibody binding to the major porin protein PorB in serogroup B Neisseria meningitidis.非表位环序列和外膜蛋白复合物的异质性改变了抗体与B群脑膜炎奈瑟菌主要孔蛋白PorB的结合。
Mol Microbiol. 2017 Sep;105(6):934-953. doi: 10.1111/mmi.13747. Epub 2017 Aug 1.
10
Identification of variable region differences in Neisseria meningitidis class 3 protein sequences among five group B serotypes.鉴定5种B群血清型脑膜炎奈瑟菌3类蛋白序列中的可变区差异
Mol Microbiol. 1992 Dec;6(23):3493-9. doi: 10.1111/j.1365-2958.1992.tb01784.x.
引用本文的文献
1
Evolution of Sequence Type 4821 Clonal Complex Meningococcal Strains in China from Prequinolone to Quinolone Era, 1972-2013.1972-2013 年中国耐喹诺酮时期以前至喹诺酮时期脑膜炎奈瑟菌 4821 型克隆复合体的序列类型演变。
Emerg Infect Dis. 2018 Apr;24(4):683-690. doi: 10.3201/eid2404.171744.
2
Characterization of TEM-1 β-Lactamase-Producing Kingella kingae Clinical Isolates.产 TEM-1 β-内酰胺酶的恋驹氏金氏杆菌临床分离株的特征分析
Antimicrob Agents Chemother. 2013 Sep;57(9):4300-4306. doi: 10.1128/AAC.00318-13. Epub 2013 Jun 24.
3
The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.脑膜炎奈瑟菌候选疫苗表面蛋白 A（NspA）与因子 H 结合，增强脑膜炎奈瑟菌对补体的抵抗力。
PLoS Pathog. 2010 Jul 29;6(7):e1001027. doi: 10.1371/journal.ppat.1001027.
4
Sequencing of the porB gene: a step toward a true characterization of Neisseria meningitidis.脑膜炎奈瑟菌porB基因测序：迈向脑膜炎奈瑟菌真正特征描述的一步。
Clin Vaccine Immunol. 2006 Oct;13(10):1087-91. doi: 10.1128/CVI.00211-06.
5
Molecular techniques for the investigation of meningococcal disease epidemiology.用于调查脑膜炎球菌病流行病学的分子技术。
Mol Biotechnol. 2001 Jun;18(2):119-34. doi: 10.1385/MB:18:2:119.
6
Population genetic and evolutionary approaches to analysis of Neisseria meningitidis isolates belonging to the ET-5 complex.用于分析属于ET-5复合体的脑膜炎奈瑟菌分离株的群体遗传学和进化方法。
J Bacteriol. 1999 Sep;181(18):5551-6. doi: 10.1128/JB.181.18.5551-5556.1999.
本文引用的文献
1
The Impact o Molecular Techniques on the Study of Meningococcal Disease.分子技术对脑膜炎球菌病研究的影响。
Methods Mol Med. 1998;15:265-91. doi: 10.1385/0-89603-498-4:265.
2
Molecular variation of meningococcal serotype 4 antigen genes.脑膜炎球菌4型血清型抗原基因的分子变异
Epidemiol Infect. 1998 Aug;121(1):95-101. doi: 10.1017/s0950268898008942.
3
Correlation between serological and sequencing analyses of the PorB outer membrane protein in the Neisseria meningitidis serotyping system.脑膜炎奈瑟菌血清分型系统中PorB外膜蛋白的血清学分析与测序分析之间的相关性
Clin Diagn Lab Immunol. 1998 May;5(3):348-54. doi: 10.1128/CDLI.5.3.348-354.1998.
4
SplitsTree: analyzing and visualizing evolutionary data.分裂树：分析与可视化进化数据
Bioinformatics. 1998;14(1):68-73. doi: 10.1093/bioinformatics/14.1.68.
5
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.多位点序列分型：一种用于鉴定致病微生物群体内克隆的便捷方法。
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3140-5. doi: 10.1073/pnas.95.6.3140.
6
Genetic heterogeneity of strains of Neisseria meningitidis belonging to serotype 22 isolated in the Czech Republic.在捷克共和国分离出的属于22血清型的脑膜炎奈瑟菌菌株的遗传异质性。
J Clin Microbiol. 1998 Feb;36(2):563-5. doi: 10.1128/JCM.36.2.563-565.1998.
7
Reactivity of the new monoclonal antibody '22' with meningococcal strains isolated from patients and carriers in Greece.新型单克隆抗体“22”与从希腊患者和携带者中分离出的脑膜炎球菌菌株的反应性。
FEMS Immunol Med Microbiol. 1997 Sep;19(1):1-5. doi: 10.1111/j.1574-695X.1997.tb01066.x.
8
9
New serotype candidate of Neisseria meningitidis.脑膜炎奈瑟菌新血清型候选菌株
Cent Eur J Public Health. 1996 Sep;4(3):169-72.
10
Antigenic diversity of meningococcal outer membrane protein PorA has implications for epidemiological analysis and vaccine design.脑膜炎球菌外膜蛋白PorA的抗原多样性对流行病学分析和疫苗设计具有重要意义。
Clin Diagn Lab Immunol. 1996 Jul;3(4):444-50. doi: 10.1128/cdli.3.4.444-450.1996.
Zotero 插件