一名产妇鞘内注射舒芬太尼和布比卡因后发生呼吸骤停。
Respiratory arrest following intrathecal injection of sufentanil and bupivacaine in a parturient.
作者信息
Katsiris S, Williams S, Leighton B L, Halpern S
机构信息
Department of Anaesthesia, Women's College Hospital, University of Toronto, Ontario, Canada.
出版信息
Can J Anaesth. 1998 Sep;45(9):880-3. doi: 10.1007/BF03012223.
PURPOSE
To present a case of respiratory arrest following the use of intrathecal sufentanil and bupivacaine for combined spinal-epidural anaesthesia in a healthy labouring parturient.
CLINICAL FEATURES
A 20-yr-old term parturient received 10 micrograms sufentanil and 2.5 mg bupivacaine intrathecally as part of a combined spinal-epidural technique for labour analgesia. She had received no previous analgesics. Twenty-three minutes after the intrathecal injection she became unresponsive and suffered a respiratory arrest. Resuscitation included manual bag/mask ventilation with oxygen and intravenous naloxone.
CONCLUSION
Respiratory arrest is a rare but potentially life-threatening complication associated with the use of intrathecal opioids for labour analgesia. Vigilance in post-procedure patient monitoring is imperative.
目的
报告一例健康产妇在腰麻-硬膜外联合麻醉中使用鞘内舒芬太尼和布比卡因后发生呼吸骤停的病例。
临床特征
一名20岁足月产妇接受了鞘内注射10微克舒芬太尼和2.5毫克布比卡因，作为腰麻-硬膜外联合分娩镇痛技术的一部分。她之前未使用过任何镇痛药。鞘内注射23分钟后，她失去意识并发生呼吸骤停。复苏措施包括用氧气进行手动面罩通气和静脉注射纳洛酮。
结论
呼吸骤停是与鞘内使用阿片类药物进行分娩镇痛相关的一种罕见但可能危及生命的并发症。术后对患者进行密切监测至关重要。
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