Aung T, Seah S K
Tan Tock Seng Hospital, Singapore.
Ophthalmology. 1998 Nov;105(11):2117-22. doi: 10.1016/S0161-6420(98)91136-8.
Previous studies have suggested that there are racial differences in the outcome of conventional filtration surgery. This study aims to evaluate the outcome of glaucoma drainage implants in Asian eyes with complicated glaucoma and to determine whether there are racial differences in the results of such implant surgery compared to previous reports in non-Asian patients.
The study design was a retrospective review of all patients with more than 6-months' follow-up after glaucoma implant surgery at the Singapore National Eye Centre between January 1993 and August 1996.
A total of 83 Asian patients with uncontrolled complicated glaucoma participated.
A total of 29 patients received Molteno implants and 54 received Baerveldt implants.
The surgical outcome was assessed in terms of final intraocular pressure (IOP), visual acuity outcome, and incidence of complications. Success was defined as final IOP less than 22 mmHg with no medications and qualified success as an IOP less than 22 mmHg with medication.
With mean follow-up of 13.41 months, success in IOP control was achieved in 73.5% of patients and qualified success in 12%. Visual acuity remained stable or improved in 85.5%. There were no patients who encountered intraoperative complications, and the incidence of serious postoperative complications was low. The most frequently observed short- and long-term postoperative complication was hyphema in 14 eyes (16.9%) and bullous keratopathy in 7 eyes (8.4%), respectively.
Glaucoma drainage implants have good outcome and visual stabilization in Asian eyes with success rates for IOP control comparable to those reported in previous studies in non-Asian eyes.
以往研究表明，传统滤过手术的结果存在种族差异。本研究旨在评估青光眼引流植入物在患有复杂性青光眼的亚洲患者眼中的效果，并确定与之前非亚洲患者的报告相比，此类植入手术的结果是否存在种族差异。
本研究设计为对1993年1月至1996年8月在新加坡国立眼科中心接受青光眼植入手术后随访超过6个月的所有患者进行回顾性研究。
共有83例患有未控制的复杂性青光眼的亚洲患者参与。
共有29例患者接受了莫尔顿植入物，54例接受了贝尔维尔德植入物。
根据最终眼压（IOP）、视力结果和并发症发生率评估手术效果。成功定义为无需药物治疗时最终眼压低于22 mmHg，合格成功定义为使用药物时眼压低于22 mmHg。
平均随访13.41个月，73.5%的患者眼压控制成功，12%的患者合格成功。85.5%的患者视力保持稳定或提高。没有患者发生术中并发症，严重术后并发症的发生率较低。最常见的短期和长期术后并发症分别是14只眼（16.9%）出现前房积血和7只眼（8.4%）出现大泡性角膜病变。
青光眼引流植入物在亚洲患者眼中效果良好且视力稳定，眼压控制成功率与之前非亚洲患者研究报告的结果相当。
