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[在马赛血液中心的献血者中对疟原虫携带者进行血清学检测的试验]

[Trial serologic detection of Plasmodium carriers among blood donors of the Centre de Transfusion Sanguine de Marseiile].

作者信息

Faugere B, Ranque J

出版信息

Rev Fr Transfus Immunohematol. 1976 Jun;19(2):349-55. doi: 10.1016/s0338-4535(76)80073-6.

Abstract

This paper is a survey of possible reservoir hosts of Plasmodium among donors of the blood transfusion Center of Marseille, by IFA test with P. falciparum and P. cynomolgi bastianellii antigens. It was found 15,7 per cent of positivity among 644 sera carefully selected during 6 months. Nord Africa and West Africa were the most dangerous countries, the former because of the great number of donors (332 of 744), the later because of the high rate (15,8 per cent) of positivity. The incidence of the say (frequency and long time) in infested countries and the interval from tate (15,8 per cent) of positivity. The incidence of the stay (frequency and long time) in infested countries and the interval from the last infestation possibility to the IFA test are very important factors. A prevention scheme is proposed: The donors staying during a very long time in infested countries will generally be used only for preparing plasma fractions by ethanol precipitations. For the others donors the blood will be used for preparing whole blood, red cells, fresh or frozen plasma, platelets and leucocytes preparation, in which a few parasites can be present, inly if a IFA test is negative 4 months after their coming back in our country.

摘要

本文通过用恶性疟原虫和食蟹猴疟原虫巴斯蒂安内利亚种抗原进行间接荧光抗体试验(IFA),对马赛输血中心供血者中疟原虫可能的储存宿主进行了调查。在6个月内精心挑选的644份血清中,发现阳性率为15.7%。北非和西非是最危险的国家,前者是因为供血者数量众多(744人中的332人),后者是因为阳性率高(15.8%)。在受感染国家停留的时间(频率和时长)以及从最后一次可能感染到进行IFA检测的间隔时间是非常重要的因素。提出了一项预防方案:长期在受感染国家停留的供血者通常仅用于通过乙醇沉淀制备血浆成分。对于其他供血者,其血液将用于制备全血、红细胞、新鲜或冷冻血浆、血小板和白细胞制剂,只有在他们回国4个月后IFA检测呈阴性时,这些制剂中才可能存在少量寄生虫。

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