Nalçaci M, Pekçelen Y
Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Turkey.
J Int Med Res. 1998 Aug-Sep;26(4):206-8. doi: 10.1177/030006059802600405.
The association between natural inhibitors of coagulation and thrombophilia was investigated in 35 patients with Behcet's disease. Antithrombin III and protein C levels were measured using synthetic chromogenic substrate methods, and protein S levels by quantitative enzyme-linked immunosorbent assay. There were no significant differences between patients and controls in plasma antithrombin III, protein C and free protein S concentrations. We conclude that there was no evidence of a primary coagulation inhibitor abnormality in patients with Behçet's disease.
在35例白塞病患者中研究了凝血天然抑制剂与血栓形成倾向之间的关联。采用合成发色底物法测定抗凝血酶III和蛋白C水平，通过定量酶联免疫吸附测定法测定蛋白S水平。患者与对照组之间的血浆抗凝血酶III、蛋白C和游离蛋白S浓度无显著差异。我们得出结论，没有证据表明白塞病患者存在原发性凝血抑制剂异常。
