Du Pasquier R, Vingerhoets F, Safran A B, Landis T
Neurology Clinic, Geneva's University Hospital, Genève, Switzerland.
Neurology. 1998 Nov;51(5):1478-80. doi: 10.1212/wnl.51.5.1478.
The authors observed a periodic downbeat nystagmus with a cycle of 3 minutes 30 seconds, beating downward for a period of 90 seconds every 2 minutes. It lasted 86 hours in a patient with severe hypomagnesemia associated with complications from scleroderma. There was no lesion on brain imaging, and an EEG performed during the nystagmus was normal, indicating that the most likely explanation for this periodic nystagmus is metabolic. This form of nystagmus may have resulted from severe hypomagnesemia, possibly associated with thiamine deficiency.
作者观察到一种周期性下跳性眼球震颤，周期为3分30秒，每2分钟向下跳动90秒。在一名患有硬皮病相关并发症的严重低镁血症患者中，这种震颤持续了86小时。脑部影像学检查未发现病变，眼球震颤期间进行的脑电图检查正常，这表明这种周期性眼球震颤最可能的原因是代谢性的。这种形式的眼球震颤可能是由严重低镁血症引起的，可能与硫胺素缺乏有关。
