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[不同生育能力程度的射精液中铁及非血红素铁蛋白代谢]

[Iron and nonheme iron protein metabolism in ejaculates with varying degrees of fertility].

作者信息

Nikolaev A A, Lutskiĭ D L, Nikolaeva N N, Lozhkina L V

出版信息

Urol Nefrol (Mosk). 1998 Sep-Oct(5):27-31.

PMID:9820043
Abstract

Spermoplasm of 21 fertile and 96 subfertile males was examined for Fe, transferrin and scaferrin the concentrations of which were compared to 14 morphofunctional and physicochemical parameters of ejaculate fertility. Fe and non-hemic spermoplasm ferroproteins are involved in male reproduction: participate in ejaculate thinning, in formation of viscosity and sperm pH, are important for normal spermatogenesis and intercellular interactions. The findings can be applied in diagnosis of male subfertility and control of ongoing treatment, hold promise for improvement of fertilizing ability of the sperm used for artificial insemination and extracorporeal fertilization.

摘要

对21名生育能力正常的男性和96名生育能力低下的男性的精浆进行了铁、转铁蛋白和铁蛋白检测,并将其浓度与精液生育能力的14个形态功能和物理化学参数进行了比较。铁和非血红素精浆铁蛋白参与男性生殖:参与精液稀释、粘度形成和精子pH值调节,对正常精子发生和细胞间相互作用至关重要。这些发现可用于男性生育力低下的诊断和治疗过程的监测,有望提高用于人工授精和体外受精的精子的受精能力。

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