非组蛋白染色体磷蛋白对组蛋白基因转录的激活作用。
Activation of histone gene transcription by nonhistone chromosomal phosphoproteins.
作者信息
Thompson J A, Stein J L, Kleinsmith L J, Stein G S
出版信息
Science. 1976 Oct 22;194(4263):428-31. doi: 10.1126/science.982025.
PMID:982025
Abstract
Hybridization analysis of RNA transcripts from HeLa S3 cell chromatin to histone complementary DNA indicates that a chromosomal phosphoprotein fraction activates transcription of histone messenger RNA sequences in vitro with chromatin from a phase in the cell cycle when histone genes are normally silent.
摘要
对来自HeLa S3细胞染色质的RNA转录本与组蛋白互补DNA进行杂交分析表明，一种染色体磷蛋白组分在体外利用细胞周期中组蛋白基因通常沉默阶段的染色质激活组蛋白信使RNA序列的转录。
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