Usubütün A, Uygur M C, Ayhan A, Toklu C, Sahin A, Ozen H, Ruacan S
Department of Pathology, Hacettepe University, School of Medicine, Ankara, Turkey.
Int Urol Nephrol. 1998;30(4):391-7. doi: 10.1007/BF02550216.
In this study histologic slides of 165 patients who were diagnosed as RCC between 1983 and 1993 were re-evaluated and each tumour was graded according to Thoenes, Fuhrman, Arner and Skinner's grading systems. According to Thoenes' system, patients with grade (G) 2 and 3 tumours had significantly shorter survival compared to patients with G 1 tumours. The survival difference between the subgroups of Fuhrman and Skinner's grading systems did not reach statistical significance. When the histologic differentiation was grouped as low grade (G 1&2) and high grade (G 3&4) tumours in Fuhrman and Skinner's systems, a statistically significant difference was noted between the groups in terms of survival.
在本研究中，对1983年至1993年间被诊断为肾细胞癌的165例患者的组织学切片进行了重新评估，并根据托内斯、富尔曼、阿纳和斯金纳的分级系统对每个肿瘤进行分级。根据托内斯系统，2级和3级肿瘤患者的生存期明显短于1级肿瘤患者。富尔曼和斯金纳分级系统亚组之间的生存差异未达到统计学意义。当在富尔曼和斯金纳系统中将组织学分化分为低级别（1级和2级）和高级别（3级和4级）肿瘤时，两组之间在生存期方面存在统计学显著差异。
