[心痛定对冠状动脉粥样硬化狭窄患者冠心病临床病程、外周循环及心肌灌注的影响]
[Adalat effects on clinical course of coronary heart disease, peripheral circulation and myocardial perfusion in patients with stenosing coronary atherosclerosis].
作者信息
Garganeeva A A, Tepliakov A T, Chernov V I, Braslavskaia T G
出版信息
Ter Arkh. 1998;70(9):61-3.
AIM
To study adalate effects on the clinical picture, systemic microcirculation and myocardial blood flow in postmyocardial infarction patients.
MATERIALS AND METHODS
Adalate was given for two weeks in a daily dose 30 mg to 17 patients with angina of effort who had survived macrofocal myocardial infarction. The examination was made with tetrapolar chest rheography, polarography, biomicroscopy, computed tomography.
RESULTS
Positive clinical changes were seen in 92% of the treated patients: the need in nitroglycerine reduced 1.8 times, muscular performance rose by 24%, skin O2 tension increased by 37.5%, central hemodynamics, microcirculation and myocardial blood flow improved noticeably.
CONCLUSION
Adalate has a good antianginal and antiischemic action due to positive hemodynamic effects.
目的
研究阿达酯对心肌梗死后患者临床表现、全身微循环及心肌血流的影响。
材料与方法
对17例曾发生大面积心肌梗死且患有劳力性心绞痛的患者给予阿达酯，每日剂量30mg，疗程两周。采用四极胸壁血流图、极谱法、生物显微镜检查及计算机断层扫描进行检查。
结果
92%的接受治疗患者出现了积极的临床变化：硝酸甘油需求量减少1.8倍，肌肉功能提高24%，皮肤氧分压增加37.5%，中心血流动力学、微循环及心肌血流明显改善。
结论
由于具有积极的血流动力学效应，阿达酯具有良好的抗心绞痛和抗缺血作用。
Zotero 插件