Bajdik C D, Gallagher R P, Hill G B, Fincham S
Cancer Control Research Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.
J Cutan Med Surg. 1998 Oct;3(2):68-73. doi: 10.1177/120347549800300203.
Sunlight is the environmental exposure most often associated with squamous cell cancer (SCC) of the skin. It can be difficult to quantify the sunlight exposure of the skin because of the different types of clothing that may be worn. The problem is simplified for studies of SCC on the skin of the head and neck, where a hat is the only type of clothing that needs to be considered.
The purpose of the study was to determine the risk for SCC of sunlight exposure on the skin of the head and neck, and the protective effect, if any, associated with wearing a hat.
A case-control study of squamous cell carcinoma of the skin was conducted amongst men in the province of Alberta, Canada. Analysis was restricted to only those cases where cancer occurred on the head or neck, and their age and sex matched controls.
Ethnicity, non-sunexposed skin colour, and hair colour each significantly affected the SCC risk. An increased SCC risk was also associated with greater cumulative sunlight exposure and with sunburns experienced during the ages 5 to 15 years. The risk associated with sunlight exposure was significantly elevated in men who reported that they had always or usually worn a hat.
As observed in previous studies, SCC on the skin of the head and neck is associated with host pigmentation, sunburns occurring in childhood, and sunlight exposure during adulthood. The risk observed for wearing a hat may be due to bias or confounding; however, hats remain an unproven means of protection against SCC on the skin of the head and neck.
阳光是与皮肤鳞状细胞癌（SCC）最常相关的环境暴露因素。由于可能穿着不同类型的衣物，很难量化皮肤的阳光暴露量。对于头颈部皮肤SCC的研究，问题得到了简化，因为帽子是唯一需要考虑的衣物类型。
本研究的目的是确定头颈部皮肤阳光暴露导致SCC的风险，以及佩戴帽子（若有）的保护作用。
在加拿大艾伯塔省的男性中开展了一项皮肤鳞状细胞癌的病例对照研究。分析仅限于癌症发生在头颈部的病例及其年龄和性别匹配的对照。
种族、非阳光暴露部位的肤色和头发颜色均显著影响SCC风险。累积阳光暴露量增加以及5至15岁期间经历过晒伤也与SCC风险增加相关。报告一直或通常戴帽子的男性中，与阳光暴露相关的风险显著升高。
如先前研究中所观察到的，头颈部皮肤的SCC与宿主色素沉着、儿童期晒伤以及成年期阳光暴露有关。观察到的戴帽子的风险可能是由于偏倚或混杂因素；然而，帽子仍然是一种未经证实的对头颈部皮肤SCC的防护手段。
