近期革兰氏阳性分离株对环丙沙星、左氧氟沙星和曲伐沙星的体外敏感性
In vitro susceptibility of recent gram-positive isolates to ciprofloxacin, levofloxacin, and trovafloxacin.
作者信息
Isenberg H D, Alperstein P, France K
机构信息
Division of Microbiology, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, New York 11042, USA.
出版信息
Diagn Microbiol Infect Dis. 1998 Oct;32(2):115-8. doi: 10.1016/s0732-8893(98)00078-9.
Gram-positive isolates (n = 290) were tested for their susceptibility to three fluoroquinolone antibiotics by standard disk-diffusion technology. Overall, 59%, 72%, and 85% were susceptible and 29%, 25%, and 11% were resistant to ciprofloxacin, levofloxacin, and trovafloxacin, respectively. Of Staphylococcus aureus isolates (n = 84), 55%, 57%, and 88% were susceptible to the three antibiotics, respectively. Staphylococcus epidermidis (n = 45), too, was more susceptible to trovafloxacin, although the differences were smaller (60%, 62%, and 78%). Of 35 Enterococcus faecalis isolates, 66% and 74% were susceptible to levofloxacin and trovafloxacin, respectively, but only 9% were susceptible to ciprofloxacin.
采用标准纸片扩散法对290株革兰氏阳性菌分离株进行了三种氟喹诺酮类抗生素的药敏试验。总体而言，对环丙沙星、左氧氟沙星和曲伐沙星敏感的菌株分别占59%、72%和85%，耐药的分别占29%、25%和11%。在84株金黄色葡萄球菌分离株中，对这三种抗生素敏感的分别占55%、57%和88%。表皮葡萄球菌（45株）对曲伐沙星也更敏感，尽管差异较小（分别为60%、62%和78%）。在35株粪肠球菌分离株中，对左氧氟沙星和曲伐沙星敏感的分别占66%和74%，但对环丙沙星敏感的仅占9%。
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