Regimbeau C, Karsenti D, Durand V, D'Alteroche L, Copie-Bergman C, Metman E H, Machet M C
Service d'Hépato-Gastroentérologie, CHU Trousseau, Tours.
Gastroenterol Clin Biol. 1998 Aug-Sep;22(8-9):720-3.
We report the fourth case of low-grade gastric MALT lymphoma associated to Helicobacter heilmannii. This spiral organism may be present in the gastric mucosa of animals where it is non pathogenic while, in humans, its presence is always associated with chronic gastritis. In this case, Helicobacter heilmannii was observed in the absence of Helicobacter pylori. Regression of endoscopic and histological lesions after Helicobacter heilmannii eradication suggests its role in gastric lymphoma. This observation underlines the need for searching for Helicobacter heilmannii by careful histological examination, in the absence of Helicobacter pylori, and the importance of its eradication in the treatment of gastric lymphoma.
我们报告了第四例与海尔曼螺杆菌相关的低级别胃黏膜相关淋巴组织淋巴瘤病例。这种螺旋状微生物可能存在于动物的胃黏膜中,在动物体内它是非致病性的,而在人类中,它的存在总是与慢性胃炎相关。在本病例中,在未检测到幽门螺杆菌的情况下发现了海尔曼螺杆菌。根除海尔曼螺杆菌后内镜及组织学病变的消退提示了其在胃淋巴瘤中的作用。这一观察结果强调了在未检测到幽门螺杆菌时通过仔细的组织学检查来寻找海尔曼螺杆菌的必要性,以及根除该菌在胃淋巴瘤治疗中的重要性。