Groisman G M, Amar M, Weiner P, Zamir D
Department of Pathology, Hillel-Yaffe Medical Center, Hadera, Israel.
Arch Pathol Lab Med. 1998 Mar;122(3):282-4.
We describe a unique case of simultaneous signet-ring histiocytes containing polyvinylpyrrolidone (mucicarminophilic histiocytosis) and hyperplastic mesothelial cells within a single supraclavicular lymph node. Both types of cells expanded the nodal sinuses and were initially suspected of being metastatic carcinoma. Histologic features suggested the correct diagnoses, which were confirmed by histochemical and immunohistochemical staining. It is important for pathologists to be aware of these phenomena, so as to avoid a misdiagnosis of metastatic carcinoma.
我们描述了一个独特的病例，在单个锁骨上淋巴结内同时存在含有聚乙烯吡咯烷酮的印戒组织细胞（嗜黏液卡红组织细胞增多症）和增生的间皮细胞。这两种类型的细胞均使淋巴结窦扩张，最初怀疑是转移性癌。组织学特征提示了正确的诊断，这通过组织化学和免疫组织化学染色得以证实。病理学家认识到这些现象很重要，以避免误诊为转移性癌。
