Al-Rawi J M, Bloxsidge J P, Elvidge J A, Jones J R
Steroids. 1976 Sep;28(3):359-75. doi: 10.1016/0039-128x(76)90046-5.
The regio- and stereo-specificity of the labelling in a series of tritiated steroid hormones has been examined by 3H n.m.r., which also yields quantitative information on the distribution of the tritium between the labelled sites. Complete analysis is thus readily achieved non-destructively. Hydrogen chemical shifts for various skeletal sites are provided for the first time. The specificity of the methods of labelling steroids with tritium by catalytic reduction, catalysed exchange, and tritiodehalogenation are discussed.
通过³H核磁共振对一系列氚标记甾体激素中标记的区域特异性和立体特异性进行了研究，该方法还能提供有关氚在标记位点间分布的定量信息。因此，可轻松无损地完成完整分析。首次给出了各种骨架位点的氢化学位移。讨论了通过催化还原、催化交换和氚代脱卤对甾体进行氚标记的方法的特异性。
