Elvidge J A, Jones J R, Saljoughian M
J Pharm Pharmacol. 1979 Aug;31(8):508-11. doi: 10.1111/j.2042-7158.1979.tb13573.x.
Propranolol, phenobartitone, diphenylhydantoin, amphetamine, imipramine and propoxyphene have been tritiated using tritiated water and platinum catalyst (from the dioxide and sodium borohydride), and the pattern of labelling has been ascertained by 3H n.m.r. spectroscopy. The results show that this exchange procedure can lead to satisfactory incorporation of tritium at 'stable' aromatic positions. For imipramine where incoroporation of tritium was low, an alternative acid-catalysed procedure was satisfactory.
已使用氚水和铂催化剂（由二氧化物和硼氢化钠制得）对普萘洛尔、苯巴比妥、苯妥英、苯丙胺、丙咪嗪和丙氧芬进行了氚标记，并通过³H核磁共振光谱确定了标记模式。结果表明，这种交换程序可使氚在“稳定”的芳香族位置实现令人满意的掺入。对于氚掺入率较低的丙咪嗪，另一种酸催化程序效果良好。
