Godfrey D G, Kilgour V
Trans R Soc Trop Med Hyg. 1976;70(3):219-24. doi: 10.1016/0035-9203(76)90043-2.
Trypanosoma (Trypanozoon) brucei includes three morphologically identical subspecies which are poorly defined by clinical behaviour; T. b. brucei does not infect man, whereas T. b. rhodesiense causes an acute, and T. b gambiense a chronic, disease. Thirty-three isolates of the complex, each of which had previously been identified on clinical or other criteria, were compared by the electrophoretic patterns of two trypanosomal enzymes, alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT). One particular ALAT pattern clearly segregated a group of human pathogens of which all except one were labelled T. b. gambiense. The exception was labelled T. b. rhodesiense, and in addition three putative T. b. gambiense isolates did not have this pattern; it is suggested that only one presents a serious anomaly. The T. b. gambiense group could also be subdivided by three ASAT patterns which coincided with known groupings based on serological criteria.
布氏锥虫（布氏锥虫属）包括三个形态相同的亚种，根据临床行为难以明确区分；布氏锥虫不感染人类，而罗德西亚锥虫引起急性疾病，冈比亚锥虫引起慢性疾病。通过两种锥虫酶，即丙氨酸转氨酶（ALAT）和天冬氨酸转氨酶（ASAT）的电泳图谱，对该复合体的33个分离株进行了比较，每个分离株此前都已根据临床或其他标准进行了鉴定。一种特定的ALAT图谱清楚地将一组人类病原体区分开来，其中除一个外，所有病原体都被标记为冈比亚锥虫。这个例外被标记为罗德西亚锥虫，此外，有三个推定的冈比亚锥虫分离株没有这种图谱；有人认为只有一个存在严重异常。冈比亚锥虫组也可以根据三种ASAT图谱进行细分，这三种图谱与基于血清学标准的已知分组一致。
