Abakumov M M, Pogodina A N, Golikov P P, Davydov B V, Fedorova N V, Nikolaeva N Iu, Marchenko V V
Vestn Khir Im I I Grek. 1998;157(4):57-61.
The biochemical assessment of severity was made in 34 patients with thoracic and abdominal gunshot wounds (12 uncomplicated; 11 with purulent, and 11 non-purulent complications). The levels of hormones, biogenic amines, lipid peroxidation (LP) indices, and antioxidant system (AOS) in serum were studied in 1, 3, 7, 14 days after admission. It was documented that the integral indices: cortisol/insulin and LP/AOS ratios were the most informative biochemical criteria for the assessment of severity of the injured patients. A high informative significance of these indices in the assessment of severity of homeostatic disturbances is pathogenetically substantiated due to stress-realizing (cortisol and free-radical LP components) and stress-limiting (insulin and AOS components) factors.
对34例胸腹部枪伤患者进行了严重程度的生化评估（12例无并发症；11例有化脓性并发症，11例有非化脓性并发症）。在入院后1、3、7、14天研究了血清中激素、生物胺、脂质过氧化（LP）指标和抗氧化系统（AOS）的水平。结果表明，综合指标：皮质醇/胰岛素和LP/AOS比值是评估受伤患者严重程度最具信息量的生化标准。由于应激实现（皮质醇和自由基LP成分）和应激限制（胰岛素和AOS成分）因素，这些指标在评估内稳态紊乱严重程度方面具有很高的信息意义，这在发病机制上得到了证实。
