Kartavenko V I, Golikov P P, Davydov B V, Andreev A A
Patol Fiziol Eksp Ter. 2004 Jan-Mar(1):8-10.
The study was made of lipid peroxidation (LPO) and antioxidant system (AOS) in 50 victims with a severe compound trauma regarding the patients' condition assessed by APACHE II scale at admission to a critical care unit. It is shown that disorders in the system LPO-AOS depend on severity of the trauma and manifest most obviously in most severe trauma, therefore the degree of LPO-AOS imbalance is a significantly informative criterion of pathobiochemical disturbances. The coefficient K, the indicator of imbalance in the system LPO-AOS, is proposed as a pathogenetically sound criterion of the assessment of the patient's condition severity in the victims with a severe compound trauma.
本研究针对50例严重复合伤患者，在其入住重症监护病房时，依据APACHE II评分评估患者病情，对脂质过氧化（LPO）和抗氧化系统（AOS）进行了研究。结果表明，LPO - AOS系统的紊乱取决于创伤的严重程度，在最严重的创伤中表现最为明显，因此LPO - AOS失衡程度是病理生化紊乱的一个重要信息指标。提出LPO - AOS系统失衡指标系数K，作为评估严重复合伤患者病情严重程度的一个基于发病机制的合理标准。
