Kent D, Noonan C P, Damato B E
St Paul's Eye Unit, Royal Liverpool University Hospital, UK.
Acta Ophthalmol Scand. 1998 Oct;76(5):584-8. doi: 10.1034/j.1600-0420.1998.760514.x.
This study reviews the results of patients referred from Ireland for treatment of an intraocular melanoma at the Ocular Oncology Service at St Paul's Eye Unit, Liverpool.
There were 57 patients with a median age of 55 years. Management included plaque radiotherapy (14), proton beam radiotherapy (17), local resection (10), endoresection (6), and enucleation (10). Fifty-two tumours involved the choroid. The tumours had a mean diameter of 11.4 mm and a mean thickness of 5.2 mm.
The follow-up period had a median of 267 days. Retention of the eye was achieved in all 47 cases who underwent conservative management. Ninety percent of patients retained a vision of counting fingers, with an acuity of 6/12 or better in 50%.
This group of patients gives an indication of the results that can be expected when uveal melanoma is managed by a variety of conservative techniques in a specialised ocular oncology service.
本研究回顾了从爱尔兰转诊至利物浦圣保罗眼科中心眼肿瘤服务部接受眼内黑色素瘤治疗的患者的治疗结果。
共有57例患者，中位年龄为55岁。治疗方法包括敷贴放射治疗（14例）、质子束放射治疗（十七例）、局部切除术（10例）、内切除术（6例）和眼球摘除术（10例）。52个肿瘤累及脉络膜。肿瘤平均直径为11.4毫米，平均厚度为5.2毫米。
随访期的中位数为267天。所有接受保守治疗的47例患者均保住了眼球。90%的患者保留了数指视力，50%的患者视力达到6/12或更好。
这组患者表明，在专业的眼肿瘤服务中，采用多种保守技术治疗葡萄膜黑色素瘤时，可以预期这样的治疗结果。
