Ndiaye P A, Ndoye P A, Seye C, Wane A, De Medeiros M, Kameny A, Ba E A, Ndiaye M R, Wade A
Clinique Ophtalmologique CHU Le Dantec-Dakar, Sénégal.
Dakar Med. 1998;43(1):21-4.
Sickle hemoglobinopathies are frequent in black population. Double heterozygous SC gives less general symptoms but ocular complications are very common. Fluorescein angiography of 20 cases are reported. All the patients had hemoglobin electrophoresis showing double heterozygous SC. Clinical investigations included fundus examination and fluorescein angiography. Laser treatment or cryotherapy were realised regarding lesions features. Vascular retinal complications were found in 75% of cases, including vitreous hemorrhage (10% of cases). There was no correlation between fundus examination and fluorescein angiography. Fluorescein angiography is useful for early diagnosis and allows preventive laser treatment.