Parsons J R, de Bruijne J A, Weiland A R
Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
Chemosphere. 1998 Oct-Nov;37(9-12):1915-22. doi: 10.1016/s0045-6535(98)00258-6.
The biphenyl-utilising Burkholderia (previously Alcaligenes) strain JB1 is also able to degrade a number of chlorinated dibenzo-p-dioxins and dibenzofurans. In this study, 4-chlorocatechol and a chlorotrihydroxydiphenyl ether were identified as metabolites of 2-chlorodibenzo-p-dioxin. 5-Chlorosalicylic acid and a chlorotrihydroxybiphenyl were metabolites of 2-chlorodibenzofuran. These results show that degradation of these compounds follows pathways in which the initial reaction is angular dioxygenation, followed by cleavage of an ether bridge. This pathway is similar to that used by dibenzofuran-degrading strains such as Sphingomonas sp. strain RW1.
利用联苯的伯克霍尔德菌（以前称为产碱菌）菌株JB1也能够降解多种氯化二苯并 - 对 - 二恶英和二苯并呋喃。在本研究中，4 - 氯邻苯二酚和一种氯代三羟基二苯醚被鉴定为2 - 氯二苯并 - 对 - 二恶英的代谢产物。5 - 氯水杨酸和一种氯代三羟基联苯是2 - 氯二苯并呋喃的代谢产物。这些结果表明，这些化合物的降解遵循初始反应为角向双加氧作用，随后醚桥断裂的途径。该途径类似于由诸如鞘氨醇单胞菌属菌株RW1等降解二苯并呋喃的菌株所使用的途径。
