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[乙型流感病毒株的干扰素诱导能力及其对外源干扰素的敏感性]

[Interferonogenic capacity of strains influenza B virus and their sensitivity to exogenous interferon].

作者信息

Solov'ev V D, Gutman N R, Manakhova L S

出版信息

Vopr Virusol. 1976 May-Jun(3):312-7.

PMID:983000
Abstract

This study is a continuation of the investgation of the influence of endogenous and exogenous interferon on influenza infection. Influenza B virus strains, both laboratory and fresh isolates, were found to be poor interferon inducers in contrast to influenza A virus strains. The study also showed that influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains from influenza A virus strains which further indicates their peculiar nature.

摘要

本研究是对内源性和外源性干扰素对流感感染影响的调查的延续。与甲型流感病毒株相比,乙型流感病毒株,无论是实验室毒株还是新分离株,都是较差的干扰素诱导剂。该研究还表明,乙型流感病毒株不仅诱导内源性干扰素的能力较差,而且对外源性干扰素也具有抗性。这一证据表明,所研究的乙型流感病毒株与甲型流感病毒株存在显著差异,这进一步表明了它们的特殊性质。

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