Solov'ev V D, Gutman N R, Manakhova L S
Vopr Virusol. 1976 May-Jun(3):312-7.
This study is a continuation of the investgation of the influence of endogenous and exogenous interferon on influenza infection. Influenza B virus strains, both laboratory and fresh isolates, were found to be poor interferon inducers in contrast to influenza A virus strains. The study also showed that influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains from influenza A virus strains which further indicates their peculiar nature.
本研究是对内源性和外源性干扰素对流感感染影响的调查的延续。与甲型流感病毒株相比，乙型流感病毒株，无论是实验室毒株还是新分离株，都是较差的干扰素诱导剂。该研究还表明，乙型流感病毒株不仅诱导内源性干扰素的能力较差，而且对外源性干扰素也具有抗性。这一证据表明，所研究的乙型流感病毒株与甲型流感病毒株存在显著差异，这进一步表明了它们的特殊性质。
