Chomik M
Arch Immunol Ther Exp (Warsz). 1981;29(1):109-4.
During interferon induction in mice in vivo with various strains of influenza A virus differences in titer of produced interferon were observed. Correlation between interferon titer and neuraminidase activity of a given influenza virus strain was noted. Similar correlation was demonstrated with virus fraction purified chromatographically and used for interferon induction. The fractions with high neuraminidase activity were good interferon inducers, whereas the fractions with undeterminable neuraminidase activity did not induce interferon in vivo.
在用不同株甲型流感病毒对小鼠进行体内干扰素诱导期间，观察到所产生的干扰素滴度存在差异。注意到给定流感病毒株的干扰素滴度与神经氨酸酶活性之间存在相关性。用色谱法纯化并用于干扰素诱导的病毒组分也证明了类似的相关性。具有高神经氨酸酶活性的组分是良好的干扰素诱导剂，而神经氨酸酶活性无法确定的组分在体内不诱导干扰素。
